We just traded in our 2005 Murano SL (loaded with all options) for a 2007 Edge SEL+ (also loaded with just about all options). Having only driven it briefly, here's an initial impression comparison:
Ride/Handling: The Edge beats the Murano handily, in my opinion. The Edge has less body roll, and provides a much smoother ride.
Interior Noise: So far, the Edge wins here by a mile. The Murano was much noisier on the road than our Edge. (Haven't had the sunroof open on the Edge yet, though).
Power: The two cars are pretty close here. I think the Murano has a bit more power, but the Edge's gearing provides better accelleration (in my opinion).
Seats: It's a split decision here. The Edge seats feel more comfortable, but there are definitely some serious tradeoffs. The Murano's power seats had more power adjustments available (power rear tilt, for example...the Edge, for some mysterious reason, has a manual adjust lever for the seatback). The Edge provides better support. But...and this is a serious one....the darned headrests on the Edge are canted way too far forward, causing my head to bounce against them no matter how I set the seatback position. It's going to require that I turn the headrests around in the Edge, which will create a less attractive seat, but eliminate the headaches. I suspect this bothers a few people, as my in-laws own a Ford Focus that they had to turn the headrests around on, too. I almost wonder if Ford designed the headrests for crash dummies instead of real people?
Navigation/Audio Unit: Again...it's another split decision. The Edge's audio provides better bass response than the Murano's Bose system...but the high end speakers are terrible when compared to the Murano. The Edge's navigation system has a clearer display than the Murano's (more pixels, I think). The Murano's Sirius radio provided a scrolling display for the song title, artist, etc. if it was too long...the Ford's system simply truncates the text. The Murano's Nav radio allows you to show your choice of the artist, genre, or song title on the top status bar at all times...and you can switch between the three by pressing the Info button. The Ford's unit seems kinda primitive in this regard. As far as I can tell, you can only see the genre displayed on the top status bar. To see the rest of the song information, you have to switch away from the navigation screen completely....and you can't do THAT while driving. The Edge does provide an auxiliary jack for your MP3 player in the console...this is (still!) not available in the Murano. All in all, I have to give this one to the Murano.
Lights/Gauges: To be honest, I haven't driven the Edge at night yet. But our Murano had HID headlights, which aren't even an option on the Edge. The Edge's instruments have a better look to them than the Murano's. I do like the "puddle" lights on the bottom of the Edge's mirrors...a cool touch. I prefer the Murano's rear view mirror, as it has the compass on it. And...the Murano displays the outside temp in the nav system's display, not the green display below as on the Edge. On this one, I haven't decided who wins just yet.
Anyway...the above are just my initial impressions.....I'm sure they'll be revised over the next few months.